Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2009-4-2
pubmed:abstractText
Ewing sarcoma is an aggressive sarcoma and is the second most common bone sarcoma in childhood. Disease-specific t(11;22) ( approximately 85-90%), t(21;22) ( approximately 5-10%), or rarer variant translocations with the involvement of chromosome 22 ( approximately 5%) are present. At the gene level, the EWSR1 gene fuses with FLI1, ERG, or other ETS transcription factor family members. Thus far, no Ewing sarcoma has been identified with a fusion to transcription factors other than ETS.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1078-0432
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
15
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2259-68
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:19318479-Adolescent, pubmed-meshheading:19318479-Adult, pubmed-meshheading:19318479-Bone Neoplasms, pubmed-meshheading:19318479-Calmodulin-Binding Proteins, pubmed-meshheading:19318479-Cloning, Molecular, pubmed-meshheading:19318479-Comparative Genomic Hybridization, pubmed-meshheading:19318479-Humans, pubmed-meshheading:19318479-In Situ Hybridization, Fluorescence, pubmed-meshheading:19318479-Interphase, pubmed-meshheading:19318479-Male, pubmed-meshheading:19318479-NFATC Transcription Factors, pubmed-meshheading:19318479-Oncogene Proteins, Fusion, pubmed-meshheading:19318479-RNA-Binding Proteins, pubmed-meshheading:19318479-Reverse Transcriptase Polymerase Chain Reaction, pubmed-meshheading:19318479-Sarcoma, Ewing, pubmed-meshheading:19318479-Sequence Analysis, DNA, pubmed-meshheading:19318479-Sequence Analysis, Protein, pubmed-meshheading:19318479-Translocation, Genetic, pubmed-meshheading:19318479-Young Adult
pubmed:year
2009
pubmed:articleTitle
The NFATc2 gene is involved in a novel cloned translocation in a Ewing sarcoma variant that couples its function in immunology to oncology.
pubmed:affiliation
Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands.
pubmed:publicationType
Journal Article