Source:http://linkedlifedata.com/resource/pubmed/id/19307680
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2009-3-24
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pubmed:abstractText |
Helicobacter pylori infection causes lifelong gastritis and is associated with the development of peptic ulcer disease, MALT lymphoma and gastric cancer. Many patients benefit from H. pylori eradication therapy. PPI-triple therapy is recommended as initial therapy. Quadruple therapy, with a PPI, bismuth, and two antibiotics, used to be recommended as second-line therapy, but can no longer be prescribed because bismuth is no longer available. Therefore, there is an urgent need for new effective rescue therapies. Levofloxacin-based therapies were suggested as an alternative to quadruple therapy. The aim of this study is to examine the efficacy and tolerability of such a one-week therapy with levofloxacin and esomeprazole combined with either amoxicillin or clarithromycin in a Dutch population.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Amoxicillin,
http://linkedlifedata.com/resource/pubmed/chemical/Clarithromycin,
http://linkedlifedata.com/resource/pubmed/chemical/Ofloxacin,
http://linkedlifedata.com/resource/pubmed/chemical/Omeprazole,
http://linkedlifedata.com/resource/pubmed/chemical/Proton Pump Inhibitors
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0300-2977
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
67
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
96-101
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pubmed:meshHeading |
pubmed-meshheading:19307680-Amoxicillin,
pubmed-meshheading:19307680-Clarithromycin,
pubmed-meshheading:19307680-Drug Administration Schedule,
pubmed-meshheading:19307680-Drug Therapy, Combination,
pubmed-meshheading:19307680-Female,
pubmed-meshheading:19307680-Helicobacter Infections,
pubmed-meshheading:19307680-Helicobacter pylori,
pubmed-meshheading:19307680-Humans,
pubmed-meshheading:19307680-Male,
pubmed-meshheading:19307680-Middle Aged,
pubmed-meshheading:19307680-Ofloxacin,
pubmed-meshheading:19307680-Omeprazole,
pubmed-meshheading:19307680-Proton Pump Inhibitors
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pubmed:year |
2009
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pubmed:articleTitle |
Seven-day PPI-triple therapy with levofloxacin is very effective for Helicobacter pylori eradication.
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pubmed:affiliation |
Department of Internal Medicine and Gastroenterology, Bernhoven Hospital, Oss, the Netherlands.
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pubmed:publicationType |
Journal Article,
Comparative Study
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