Linked Life Data

19303759

Source:http://linkedlifedata.com/resource/pubmed/id/19303759

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-6-5
pubmed:abstractText
As the proper development of germlines is vital for species preservation, elaborative, regulatory systems for gene expression must operate in germlines. One such system is RNA silencing, sequence-specific gene silencing mechanisms mediated by small RNAs of 20-30 nucleotides long. Indeed, recent studies have revealed that various types of small RNAs are expressed germline-specifically. To preserve the germlines, they collaborate with Argonaute proteins, the catalytic engines in RNA silencing, to inhibit injurious, parasitic genes, transcriptionally or post-transcriptionally. This chapter summarizes the exquisite collaboration of Argonaute proteins with small RNAs in the RNA silencing mechanisms necessary for germline survival in Drosophila and mice.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1879-0410
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
21
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
426-34
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
RNA silencing in germlines--exquisite collaboration of Argonaute proteins with small RNAs for germline survival.
pubmed:affiliation
Keio University School of Medicine, Tokyo 160-8582, Japan. siomim@sc.itc.keio.ac.jp
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't