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rdf:type |
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lifeskim:mentions |
umls-concept:C0017337,
umls-concept:C0021289,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0040649,
umls-concept:C0162326,
umls-concept:C0205112,
umls-concept:C0225828,
umls-concept:C0380603,
umls-concept:C1167622,
umls-concept:C1314939,
umls-concept:C1335858
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pubmed:issue |
13-14
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pubmed:dateCreated |
2009-4-20
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pubmed:abstractText |
The identification of transcription factors that regulate the transcription of the fibroblast growth factor-2 (FGF-2) gene has facilitated the understanding of the etiology of cardiovascular diseases. The purpose of this study was to determine the molecular mechanism underlying the activation of FGF-2 gene transcription in cardiomyocytes from neonatal rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1879-0631
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
27
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
421-7
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pubmed:meshHeading |
pubmed-meshheading:19302822-Animals,
pubmed-meshheading:19302822-Animals, Newborn,
pubmed-meshheading:19302822-Base Sequence,
pubmed-meshheading:19302822-Binding Sites,
pubmed-meshheading:19302822-Cell Nucleus,
pubmed-meshheading:19302822-Cells, Cultured,
pubmed-meshheading:19302822-Chromatin Immunoprecipitation,
pubmed-meshheading:19302822-Electrophoretic Mobility Shift Assay,
pubmed-meshheading:19302822-Fibroblast Growth Factor 2,
pubmed-meshheading:19302822-Gene Expression Regulation,
pubmed-meshheading:19302822-Molecular Sequence Data,
pubmed-meshheading:19302822-Mutation,
pubmed-meshheading:19302822-Myocytes, Cardiac,
pubmed-meshheading:19302822-Promoter Regions, Genetic,
pubmed-meshheading:19302822-Protein Interaction Domains and Motifs,
pubmed-meshheading:19302822-Rats,
pubmed-meshheading:19302822-Sp1 Transcription Factor,
pubmed-meshheading:19302822-Transcription, Genetic,
pubmed-meshheading:19302822-Transfection
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pubmed:year |
2009
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pubmed:articleTitle |
Involvement of Sp1 binding sequences in basal transcription of the rat fibroblast growth factor-2 gene in neonatal cardiomyocytes.
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pubmed:affiliation |
Laboratory of Pharmacology and Toxicology, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510080, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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