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pubmed-article:19299500pubmed:abstractTextTh2 cytokines play an important role in allergic diseases. These cytokines activate signal transduction pathways, including Janus kinase/signal transducer and activator of transcription (STAT) signaling. Although the suppressor of cytokine signaling (SOCS) family protein, a negative regulator of the Janus kinase/STAT signaling pathway, contributes to helper T cell differentiation during immune responses, the role of SOCS proteins within the structural cells of a target organ has not been clarified in allergy.lld:pubmed
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pubmed-article:19299500pubmed:articleTitlePulmonary suppressor of cytokine signaling-1 induced by IL-13 regulates allergic asthma phenotype.lld:pubmed
pubmed-article:19299500pubmed:affiliationResearch Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.lld:pubmed
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