rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2009-5-21
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pubmed:abstractText |
Th2 cytokines play an important role in allergic diseases. These cytokines activate signal transduction pathways, including Janus kinase/signal transducer and activator of transcription (STAT) signaling. Although the suppressor of cytokine signaling (SOCS) family protein, a negative regulator of the Janus kinase/STAT signaling pathway, contributes to helper T cell differentiation during immune responses, the role of SOCS proteins within the structural cells of a target organ has not been clarified in allergy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-13,
http://linkedlifedata.com/resource/pubmed/chemical/SOCS1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/STAT6 Transcription Factor,
http://linkedlifedata.com/resource/pubmed/chemical/STAT6 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Socs1 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Stat6 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Suppressor of Cytokine Signaling...
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1535-4970
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pubmed:author |
pubmed-author:AizawaHisamichiH,
pubmed-author:BlackJudith LJL,
pubmed-author:BurgessJanette KJK,
pubmed-author:FukuyamaSatoruS,
pubmed-author:HoshinoTomoakiT,
pubmed-author:InoueHiromasaH,
pubmed-author:KuboMasatoM,
pubmed-author:MatsumotoKoichiroK,
pubmed-author:MatsumotoTakafumiT,
pubmed-author:McKenzieAndrew N JAN,
pubmed-author:MoriwakiAtsushiA,
pubmed-author:NakanishiYoichiY,
pubmed-author:NakanoTakakoT,
pubmed-author:OliverBrian G GBG,
pubmed-author:TanakaHiroyukiH,
pubmed-author:TanakaKentaroK,
pubmed-author:YoshimuraAkihikoA
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
179
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
992-8
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pubmed:meshHeading |
pubmed-meshheading:19299500-Animals,
pubmed-meshheading:19299500-Asthma,
pubmed-meshheading:19299500-Cells, Cultured,
pubmed-meshheading:19299500-Disease Models, Animal,
pubmed-meshheading:19299500-Humans,
pubmed-meshheading:19299500-Interleukin-13,
pubmed-meshheading:19299500-Mice,
pubmed-meshheading:19299500-Myocytes, Smooth Muscle,
pubmed-meshheading:19299500-STAT6 Transcription Factor,
pubmed-meshheading:19299500-Suppressor of Cytokine Signaling Proteins,
pubmed-meshheading:19299500-Th2 Cells,
pubmed-meshheading:19299500-Up-Regulation
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pubmed:year |
2009
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pubmed:articleTitle |
Pulmonary suppressor of cytokine signaling-1 induced by IL-13 regulates allergic asthma phenotype.
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pubmed:affiliation |
Research Institute for Diseases of the Chest, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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