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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
2009-4-8
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pubmed:abstractText |
Molecular screening for BRCA1 and BRCA2 mutations is now an established component of risk evaluation and management of familial breast cancer. Features of hereditary breast cancer include an early age-of-onset and over-representation of the 'triple-negative' phenotype (negative for estrogen-receptor, progesterone-receptor and HER2). The decision to offer genetic testing to a breast cancer patient is usually based on her family history, but in the absence of a family history of cancer, some women may qualify for testing based on the age-of-onset and/or the pathologic features of the breast cancer.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-10359546,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-10413426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-10728676,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-10782928,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-10788334,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-10827109,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-11410514,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-12048272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-14519755,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-15041722,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-15381934,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-15987465,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-16033833,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-17063074,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-17116942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-17406573,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-8622094,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19298662-9792861
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2407
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pubmed:author |
pubmed-author:BrooksKaren AKA,
pubmed-author:CohenStephanieS,
pubmed-author:DesaiDaminiD,
pubmed-author:DonenbergTaliaT,
pubmed-author:HammondLyn SLS,
pubmed-author:MillerJudithJ,
pubmed-author:NarodSteven ASA,
pubmed-author:PilarskiRobert TRT,
pubmed-author:ROSSJ KJK,
pubmed-author:RoyerRobertR,
pubmed-author:ShapiroCharlesC,
pubmed-author:TenenholzBeverlyB,
pubmed-author:YoungS RSR,
pubmed-author:ZandvakiliInukI
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pubmed:issnType |
Electronic
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pubmed:volume |
9
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
86
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pubmed:dateRevised |
2010-9-23
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pubmed:meshHeading |
pubmed-meshheading:19298662-Adult,
pubmed-meshheading:19298662-BRCA1 Protein,
pubmed-meshheading:19298662-Breast Neoplasms,
pubmed-meshheading:19298662-DNA Mutational Analysis,
pubmed-meshheading:19298662-Female,
pubmed-meshheading:19298662-Gene Frequency,
pubmed-meshheading:19298662-Genetic Testing,
pubmed-meshheading:19298662-Humans,
pubmed-meshheading:19298662-Mutation,
pubmed-meshheading:19298662-Receptor, erbB-2,
pubmed-meshheading:19298662-Receptors, Estrogen,
pubmed-meshheading:19298662-Receptors, Progesterone,
pubmed-meshheading:19298662-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
The prevalence of BRCA1 mutations among young women with triple-negative breast cancer.
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pubmed:affiliation |
Women's College Research Institute, Department of Public Health, The University of Toronto, Toronto, Canada. sryoung37@aol.com
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pubmed:publicationType |
Journal Article
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