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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
1991-11-7
|
| pubmed:abstractText |
We studied results of a "lookback" program involving laboratory testing and interviews of 133 recipients of prior donations from blood donors seropositive for human T-lymphotropic virus types I and II (HTLV-I/II) identified at 28 American Red Cross blood centers. The study was designed to explore the natural course of posttransfusion HTLV-I/II infection among individuals who received blood components from donors subsequently identified as being HTLV-I/II seropositive. Seventeen recipients were seropositive, an apparent transmission rate of 12.8%. Red blood cells and platelets were the implicated components, and red blood cells that were less than 6 days old had a transmission efficiency of 80%. Virus typing enabled documentation of primary and secondary transfusion transmission of HTLV-I and HTLV-II, including the direct transmission of HTLV-II by a donor with a history of intravenous drug use. We conclude that transfusion transmission of HTLV-I/II to approximately 700 recipients per year occurred in the United States before routine donor testing began in 1988.
|
| pubmed:grant | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
AIM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
0003-9926
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
151
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
2043-8
|
| pubmed:dateRevised |
2007-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:1929693-Adolescent,
pubmed-meshheading:1929693-Adult,
pubmed-meshheading:1929693-Aged,
pubmed-meshheading:1929693-Blood Transfusion,
pubmed-meshheading:1929693-Child,
pubmed-meshheading:1929693-Erythrocyte Transfusion,
pubmed-meshheading:1929693-Female,
pubmed-meshheading:1929693-HTLV-I Infections,
pubmed-meshheading:1929693-HTLV-II Infections,
pubmed-meshheading:1929693-Humans,
pubmed-meshheading:1929693-Male,
pubmed-meshheading:1929693-Mass Screening,
pubmed-meshheading:1929693-Middle Aged,
pubmed-meshheading:1929693-Platelet Transfusion,
pubmed-meshheading:1929693-Questionnaires,
pubmed-meshheading:1929693-Retrospective Studies,
pubmed-meshheading:1929693-Risk Factors,
pubmed-meshheading:1929693-Serologic Tests
|
| pubmed:year |
1991
|
| pubmed:articleTitle |
Transmission of human T-lymphotropic virus types I and II by blood transfusion. A retrospective study of recipients of blood components (1983 through 1988). The American Red Cross HTLV-I/II Collaborative Study Group.
|
| pubmed:affiliation |
American Red Cross Blood Services, Rockville, MD 20855.
|
| pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
|