|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0002078,
umls-concept:C0023688,
umls-concept:C0037638,
umls-concept:C0205088,
umls-concept:C0311404,
umls-concept:C0441712,
umls-concept:C0443286,
umls-concept:C0597565,
umls-concept:C1710028,
umls-concept:C1879547,
umls-concept:C1880497,
umls-concept:C1996904
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|
pubmed:issue |
8
|
|
pubmed:dateCreated |
2009-4-9
|
|
pubmed:abstractText |
FeCl(2) catalyzes the oxidative C-C cross-coupling of tertiary amines with terminal alkynes into propargylamines using (t-BuO)(2) as oxidant. The reaction can be applied to aromatic and aliphatic amines and alkynes without solvent. High chemoselectivity for aminomethyl groups is due to a steric factor.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
1523-7052
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
16
|
|
pubmed:volume |
11
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1701-4
|
|
pubmed:meshHeading |
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Chemoselective C-H bond activation: ligand and solvent free iron-catalyzed oxidative C-C cross-coupling of tertiary amines with terminal alkynes. Reaction scope and mechanism.
|
|
pubmed:affiliation |
Laboratoire de glycochimie et de synthese asymetrique (LGSA), Swiss Federal Institute of Technology of Lausanne (EPFL), CH 1015 Lausanne, Switzerland.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
