Linked Life Data

19293918

Source:http://linkedlifedata.com/resource/pubmed/id/19293918

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2009-3-18
pubmed:abstractText
The loss of organization of the corneal collagen lattice induced by photothermal effects was analyzed by using second-harmonic generation (SHG) imaging. Porcine cornea samples were treated with low-power laser irradiation in order to get localized areas of tissue disorganization. The disorder induced within the irradiated area of corneal stroma was quantified by means of Discrete Fourier Transform, auto-correlation and entropy analyses of the SHG images. Polarization modulated SHG measurements allowed to probe the changes in the structural anisotropy of sub-micron hierarchical levels of the stromal collagen. Our results emphasize the great potential of the SHG imaging to detect subtle modifications in the collagen assembly. The proposed analytical methods may be used to track several genetic, pathologic, accidental or surgical-induced disorder states of biological tissues.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1094-4087
pubmed:author
pubmed:copyrightInfo
(c) 2008 Optical Society of America
pubmed:issnType
Electronic
pubmed:day
16
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
4868-78
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Photothermally-induced disordered patterns of corneal collagen revealed by SHG imaging.
pubmed:affiliation
Istituto di Fisica Applicata Nello Carrara, Consiglio Nazionale delle Ricerche, Via Madonna del Piano 10, Sesto Fiorentino, I-50019, Italy.
pubmed:publicationType
Journal Article