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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-4-3
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pubmed:abstractText |
Adequate relief (AR) of irritable bowel syndrome (IBS) symptoms (IBS-AR) has been used as a primary end point in many randomized controlled trials of IBS and is considered by the Rome III committee to be an acceptable primary end point. However, controversy exists on whether baseline severity confounds the effect of the treatment outcome. The aim (1) is to compare a subjective report of IBS-AR with global assessment of improvement (IBS-GAI), change in IBS symptom severity scale (IBS-SSS), and IBS quality of life (IBS-QOL); (2) to explore whether initial IBS symptom severity influences the ability of these outcome measures to detect differences post treatment; and (3) to determine whether psychological symptoms influence the sensitivity of these measures, in a randomized controlled treatment trial.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-10468696,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-10520844,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-10580921,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-10744088,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-10763950,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-11485506,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-11569692,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-12692051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-12870789,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-13688369,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-15000272,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-15082584,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-15765393,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-16020489,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-16233998,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-16573774,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-16678561,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-16678567,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-16842448,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-17040359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-17227528,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-19293789,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-19888249,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-9146781,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-9512138,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19293784-9602985
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1572-0241
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pubmed:author |
pubmed-author:ConboyLisa ALA,
pubmed-author:DrossmanDouglas ADA,
pubmed-author:FriedlanderElizabethE,
pubmed-author:HuRongR,
pubmed-author:JacobsonEric EEE,
pubmed-author:KaptchukTed JTJ,
pubmed-author:KellyJohn MJM,
pubmed-author:KerrCatherine ECE,
pubmed-author:LemboAnthony JAJ,
pubmed-author:PassosMaria C FMC,
pubmed-author:QuiltyMary TMT
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pubmed:issnType |
Electronic
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pubmed:volume |
104
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
912-9
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pubmed:dateRevised |
2010-9-7
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pubmed:meshHeading |
pubmed-meshheading:19293784-Acupuncture Therapy,
pubmed-meshheading:19293784-Adolescent,
pubmed-meshheading:19293784-Adult,
pubmed-meshheading:19293784-Aged,
pubmed-meshheading:19293784-Female,
pubmed-meshheading:19293784-Follow-Up Studies,
pubmed-meshheading:19293784-Humans,
pubmed-meshheading:19293784-Irritable Bowel Syndrome,
pubmed-meshheading:19293784-Male,
pubmed-meshheading:19293784-Middle Aged,
pubmed-meshheading:19293784-Pain Measurement,
pubmed-meshheading:19293784-Prospective Studies,
pubmed-meshheading:19293784-Quality of Life,
pubmed-meshheading:19293784-Questionnaires,
pubmed-meshheading:19293784-Single-Blind Method,
pubmed-meshheading:19293784-Treatment Outcome,
pubmed-meshheading:19293784-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
Adequate relief in a treatment trial with IBS patients: a prospective assessment.
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pubmed:affiliation |
Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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