rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
2009-6-4
|
pubmed:abstractText |
The iodothyronine deiodinases D1, D2, and D3 enable tissue-specific adaptation of thyroid hormone levels in response to various conditions, such as hypothyroidism or fasting. The possible expression of D2 mRNA in skeletal muscle is intriguing because this enzyme could play a role in systemic as well as local T3 production.
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pubmed:commentsCorrections |
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
1945-7197
|
pubmed:author |
pubmed-author:BurggraafJacobusJ,
pubmed-author:CorssmitEleonora PEP,
pubmed-author:FliersEricE,
pubmed-author:HeemstraKaren AKA,
pubmed-author:RomijnJohannes AJA,
pubmed-author:SerlieMireille JMJ,
pubmed-author:SmitJohannes WJW,
pubmed-author:SoetersMaarten RMR,
pubmed-author:VisserTheo JTJ,
pubmed-author:van DoornMartijn BMB,
pubmed-author:van der KlaauwAgatha AAA
|
pubmed:issnType |
Electronic
|
pubmed:volume |
94
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
2144-50
|
pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19293265-Carcinoma,
pubmed-meshheading:19293265-Fasting,
pubmed-meshheading:19293265-Female,
pubmed-meshheading:19293265-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:19293265-Hormone Replacement Therapy,
pubmed-meshheading:19293265-Humans,
pubmed-meshheading:19293265-Hypothyroidism,
pubmed-meshheading:19293265-Insulin,
pubmed-meshheading:19293265-Iodide Peroxidase,
pubmed-meshheading:19293265-Lidocaine,
pubmed-meshheading:19293265-Male,
pubmed-meshheading:19293265-Middle Aged,
pubmed-meshheading:19293265-Muscle, Skeletal,
pubmed-meshheading:19293265-Thyroid Hormones,
pubmed-meshheading:19293265-Thyroid Neoplasms,
pubmed-meshheading:19293265-Thyroidectomy
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pubmed:year |
2009
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pubmed:articleTitle |
Type 2 iodothyronine deiodinase in skeletal muscle: effects of hypothyroidism and fasting.
|
pubmed:affiliation |
Leiden University Medical Centre, Department of Endocrinology and Metabolic Diseases, P.O. Box 9600, Leiden 2300 RC, The Netherlands. k.a.heemstra@lumc.nl
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pubmed:publicationType |
Journal Article,
Clinical Trial
|