pubmed:abstractText |
Current four dimensional (4D) computed tomography (CT) reconstruction techniques are retrospectively created based on either the phase or displacement of the respiratory signal. Both techniques have known limitations which cause clinically significant motion artifacts in 4D CT images. These artifacts, which appear as undefined or irregular boundaries in the 4D CT images, cause systematic errors in patient contouring and dose calculations. The aim of this work was to evaluate the reproducibility of tumor position as a function of displacement, phase, and velocity of the respiratory signal, respectively, in order to determine the optimum parameter or combination of parameters to use in order to minimize artifacts in 4D CT images or to accurately deliver radiation to relevant structures during treatment.
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pubmed:affiliation |
Department of Radiation Oncology, Radiation Physics Division, Stanford University Cancer Center, 875 Blake Wilbur Drive, Stanford, California 94305-5847, USA. ulangner@stanford.edu
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