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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1-3
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pubmed:dateCreated |
2009-6-2
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pubmed:abstractText |
Ghrelin is a gastric acyl-peptide that has been identified as an endogenous ligand for the growth hormone secretagogue receptor. It has been reported to have cardioprotective activities independent of growth hormone release. We investigated the effect of ghrelin on apoptosis induced by high glucose and sodium palmitate and the mechanisms underlying the cardioprotective activities of ghrelin.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1873-1686
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
5
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pubmed:volume |
155
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
62-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:19289146-Animals,
pubmed-meshheading:19289146-Apoptosis,
pubmed-meshheading:19289146-Blotting, Western,
pubmed-meshheading:19289146-Caspase 3,
pubmed-meshheading:19289146-Cells, Cultured,
pubmed-meshheading:19289146-Enzyme Inhibitors,
pubmed-meshheading:19289146-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:19289146-Ghrelin,
pubmed-meshheading:19289146-Glucose,
pubmed-meshheading:19289146-Male,
pubmed-meshheading:19289146-NF-kappa B,
pubmed-meshheading:19289146-Palmitic Acid,
pubmed-meshheading:19289146-Phosphatidylinositol 3-Kinases,
pubmed-meshheading:19289146-Proto-Oncogene Proteins c-akt,
pubmed-meshheading:19289146-Rats,
pubmed-meshheading:19289146-Reactive Oxygen Species,
pubmed-meshheading:19289146-Signal Transduction,
pubmed-meshheading:19289146-Sweetening Agents
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pubmed:year |
2009
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pubmed:articleTitle |
Ghrelin inhibits apoptosis induced by high glucose and sodium palmitate in adult rat cardiomyocytes through the PI3K-Akt signaling pathway.
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pubmed:affiliation |
Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, Shanghai 200040, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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