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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2009-4-24
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pubmed:abstractText |
Chronic pancreatitis (CP) and pancreatic adenocarcinoma (pCA) are associated with risk factors such as alcohol intake and tobacco smoking. Microsomal epoxide hydrolase (EPHX1) is a phase II detoxifying enzyme capable of tobacco-borne toxicant inactivation. We studied the role of the EPHX1 c.337T>C (p.Y113H) variant, whichleads to altered enzyme activity, in pancreatic diseases.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1536-4828
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pubmed:author |
pubmed-author:DrenthJoost P HJP,
pubmed-author:HalangkJulianeJ,
pubmed-author:JansenJan B M JJB,
pubmed-author:KageAndreasA,
pubmed-author:KeimVolkerV,
pubmed-author:LöhrMatthiasM,
pubmed-author:LochsHerbertH,
pubmed-author:OckengaJohannJ,
pubmed-author:OettleHelmutH,
pubmed-author:PfützerRoland HRH,
pubmed-author:PostCoraC,
pubmed-author:RosendahlJonasJ,
pubmed-author:SchulzHans-UlrichHU,
pubmed-author:StrunckSebastianS,
pubmed-author:WittHeikoH
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pubmed:issnType |
Electronic
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e97-e101
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pubmed:dateRevised |
2010-5-21
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pubmed:meshHeading |
pubmed-meshheading:19287329-Acute Disease,
pubmed-meshheading:19287329-Adenocarcinoma,
pubmed-meshheading:19287329-Adolescent,
pubmed-meshheading:19287329-Adult,
pubmed-meshheading:19287329-Aged,
pubmed-meshheading:19287329-Child,
pubmed-meshheading:19287329-Epoxide Hydrolases,
pubmed-meshheading:19287329-Female,
pubmed-meshheading:19287329-Gene Frequency,
pubmed-meshheading:19287329-Genetic Variation,
pubmed-meshheading:19287329-Genotype,
pubmed-meshheading:19287329-Germany,
pubmed-meshheading:19287329-Humans,
pubmed-meshheading:19287329-Male,
pubmed-meshheading:19287329-Middle Aged,
pubmed-meshheading:19287329-Mutation, Missense,
pubmed-meshheading:19287329-Netherlands,
pubmed-meshheading:19287329-Pancreatic Diseases,
pubmed-meshheading:19287329-Pancreatic Neoplasms,
pubmed-meshheading:19287329-Pancreatitis, Alcoholic,
pubmed-meshheading:19287329-Pancreatitis, Chronic,
pubmed-meshheading:19287329-Risk Factors,
pubmed-meshheading:19287329-Young Adult
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pubmed:year |
2009
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pubmed:articleTitle |
The role of epoxide hydrolase Y113H gene variant in pancreatic diseases.
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pubmed:affiliation |
Department of Gastroenterology, Hepatology & Endocrinology, Charité, Campus Mitte, Germany. johann.ockenga@klinikum-bremen-mitte.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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