Source:http://linkedlifedata.com/resource/pubmed/id/19284728
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2009-4-8
|
| pubmed:abstractText |
Since attention has been paid to the use of multiwalled carbon nanotubes (MWCNTs) as biomaterials in contact with bone, it is critical to understand the reaction of bone cells to MWCNTs. We show that MWCNTs inhibit osteoclastic bone resorption in vivo and that MWCNTs inhibit osteoclastic differentiation and suppressed a transcription factor essential for osteoclastogenesis in vitro. These results suggest that MWCNTs have beneficial effects on bones when they are used as biomaterials.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
1530-6992
|
| pubmed:author |
pubmed-author:AokiKaoruK,
pubmed-author:EndoMorinobuM,
pubmed-author:IshiharaAkihiroA,
pubmed-author:KatoHiroyukiH,
pubmed-author:KobayashiYasuhiroY,
pubmed-author:MaedaKazuhiroK,
pubmed-author:MizoguchiToshihideT,
pubmed-author:NakamuraHiroakiH,
pubmed-author:NaritaNobuyoN,
pubmed-author:OzawaHidehiroH,
pubmed-author:SaitoNaotoN,
pubmed-author:SimizuMasayukiM,
pubmed-author:TakahashiNaoyukiN,
pubmed-author:UdagawaNobuyukiN,
pubmed-author:UsuiYukiY
|
| pubmed:issnType |
Electronic
|
| pubmed:volume |
9
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1406-13
|
| pubmed:meshHeading | |
| pubmed:year |
2009
|
| pubmed:articleTitle |
Multiwalled carbon nanotubes specifically inhibit osteoclast differentiation and function.
|
| pubmed:affiliation |
Department of Orthopedic Surgery, Shinshu University School of Medicine, 3-1-1 Asahi Matsumoto, Nagano, Japan.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|