Source:http://linkedlifedata.com/resource/pubmed/id/19284297
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2009-3-30
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pubmed:abstractText |
Tuberculosis (TB) remains a major health problem affecting millions of people worldwide. One-third of the world's population is infected with Mycobacterium tuberculosis, the etiologic agent of TB. A simple and rapid method to diagnose TB is urgently needed to be developed. The procedure of systematic evolution of ligands by exponential enrichment (SELEX) is a method in which single-stranded oligonucleotides (called aptamers) are selected from a wide variety of sequences, based on their interaction with a target molecule. Aptamers have been used in numerous investigations as therapeutic or diagnostic tools.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1434-6621
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
405-11
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pubmed:meshHeading |
pubmed-meshheading:19284297-Antigens, Bacterial,
pubmed-meshheading:19284297-Aptamers, Nucleotide,
pubmed-meshheading:19284297-Mycobacterium tuberculosis,
pubmed-meshheading:19284297-SELEX Aptamer Technique,
pubmed-meshheading:19284297-Sensitivity and Specificity,
pubmed-meshheading:19284297-Tuberculosis
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pubmed:year |
2009
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pubmed:articleTitle |
The selection and application of ssDNA aptamers against MPT64 protein in Mycobacterium tuberculosis.
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pubmed:affiliation |
Shanghai Key Laboratory of Tuberculosis, Shanghai Pulmonary Hospital, Affiliated to Tongji University, Shanghai, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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