Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-3-11
pubmed:abstractText
Hematopoietic stem cells are at the foundation of the blood system. Their study is not only relevant to the understanding of the basic cellular mechanisms of self-renewal, lineage commitment, and differentiation, but they have also been the target of intense clinical research into the causes of leukemia and the exploitation of these cells for cell replacement therapies. The basic mechanisms of hematopoietic stem cell regulation become evident in the way these cells are first generated and expanded during development. Isolating and analyzing hematopoietic stem cells from the embryo is therefore of direct clinical importance.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1064-3745
pubmed:author
pubmed:issnType
Print
pubmed:volume
538
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
335-46
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Analysis of the mouse placenta as a hematopoietic stem cell niche.
pubmed:affiliation
Department of Haematology, Cambridge Institute for Medical Research, University of Cambridge, Hills Road, Cambridge, CB2 0XY, UK. ko268@cam.ac.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't