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rdf:type |
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lifeskim:mentions |
umls-concept:C0009450,
umls-concept:C0011155,
umls-concept:C0015392,
umls-concept:C0035333,
umls-concept:C0205307,
umls-concept:C0681850,
umls-concept:C0936012,
umls-concept:C1550501,
umls-concept:C1550587,
umls-concept:C1706203,
umls-concept:C1707455,
umls-concept:C2349001,
umls-concept:C2697811,
umls-concept:C2699740
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pubmed:dateCreated |
2009-3-11
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pubmed:abstractText |
To test the following hypotheses: (1) eyes from individuals with human immunodeficiency virus (HIV) have electrophysiologic abnormalities that manifest as multifocal electroretinogram (mfERG) abnormalities; (2) the retinal effects of HIV in immune-competent HIV individuals differ from the effects in immune-incompetent HIV individuals; (3) strong machine learning classifiers (MLCs), like support vector machine (SVM), can learn to use mfERG abnormalities in the second-order kernel (SOK) to distinguish HIV from normal eyes; and (4) the mfERG abnormalities fall into patterns that can be discerned by MLCs. We applied a supervised MLC, SVM, to determine if mfERGs in eyes from patients with HIV differ from mfERGs in HIV-negative controls.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-10343810,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-10369585,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-10509661,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-10645387,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-10925245,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-11006263,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-11222541,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-11510112,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-11773027,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-12407155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-12678274,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-1370189,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-15031174,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-15326133,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-15452093,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-15573947,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-15733991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-1604830,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-16186350,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-16310457,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-16534052,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-16564817,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-16876510,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-16949855,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-17031295,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-17212991,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-17324696,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-18046236,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-18280451,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-18427600,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-2522276,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-3203132,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-7872396,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-8023875,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-8056511,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-8206718,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-8280686,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-8610794,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-8862052,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-8960726,
http://linkedlifedata.com/resource/pubmed/commentcorrection/19277235-9375578
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:issn |
1545-6110
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
106
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
196-204; discussion 204-5
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:19277235-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:19277235-Area Under Curve,
pubmed-meshheading:19277235-Artificial Intelligence,
pubmed-meshheading:19277235-CD4 Lymphocyte Count,
pubmed-meshheading:19277235-Electroretinography,
pubmed-meshheading:19277235-Eye Infections, Viral,
pubmed-meshheading:19277235-Female,
pubmed-meshheading:19277235-HIV Infections,
pubmed-meshheading:19277235-Humans,
pubmed-meshheading:19277235-Male,
pubmed-meshheading:19277235-Middle Aged,
pubmed-meshheading:19277235-ROC Curve,
pubmed-meshheading:19277235-Retina,
pubmed-meshheading:19277235-Retinal Diseases,
pubmed-meshheading:19277235-Retinitis
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pubmed:year |
2008
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pubmed:articleTitle |
Analysis with support vector machine shows HIV-positive subjects without infectious retinitis have mfERG deficiencies compared to normal eyes.
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pubmed:affiliation |
Ophthalmic Informatics Laboratory, University of California at San Diego, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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