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pubmed-article:19276448pubmed:abstractTextThe E6 and E7 genes of human papillomavirus type 16 (HPV16) encode oncoproteins that bind and degrade p53 and retinoblastoma (pRb) tumor suppressors, respectively. We examined the effects of repressing E6 and E7 oncogene expression on the transformed phenotype of HPV16-positive oropharyngeal cancer cell lines.lld:pubmed
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pubmed-article:19276448pubmed:articleTitleE6 and e7 gene silencing and transformed phenotype of human papillomavirus 16-positive oropharyngeal cancer cells.lld:pubmed
pubmed-article:19276448pubmed:affiliationDepartment of Medical Oncology, Yale University School of Medicine, New Haven, CT 06520, USA.lld:pubmed
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