Source:http://linkedlifedata.com/resource/pubmed/id/19275579
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2009-3-11
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pubmed:abstractText |
We focus on the role of Vpr in inducing DNA double-strand breaks (DSBs) in the host cell. Based on the summarized findings of Vpr-induced DSBs and the finding of Vpr in the plasma of HIV-1-positive patients, we discuss the roles of Vpr in viral infection, especially viral infection of resting macrophages. We also describe the possible involvement of Vpr in non-AIDS-defining cancers, which represent an emerging crisis in HIV-1-positive patients.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1873-4251
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
109-13
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pubmed:meshHeading | |
pubmed:year |
2009
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pubmed:articleTitle |
Vpr-induced DNA double-strand breaks: molecular mechanism and biological relevance.
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pubmed:affiliation |
Department of Intractable Diseases, Research Institute, International Medical Center of Japan, Toyama, Shinuku-ku, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Review
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