pubmed-article:19275156 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:19275156 | lifeskim:mentions | umls-concept:C0011209 | lld:lifeskim |
pubmed-article:19275156 | lifeskim:mentions | umls-concept:C1450054 | lld:lifeskim |
pubmed-article:19275156 | pubmed:issue | 12 | lld:pubmed |
pubmed-article:19275156 | pubmed:dateCreated | 2009-3-25 | lld:pubmed |
pubmed-article:19275156 | pubmed:abstractText | Dumbbell-like Au-Fe(3)O(4) nanoparticles (NPs) were made and coupled with Herceptin and a platin complex. The platin-Au-Fe(3)O(4)-Herceptin NPs act as a target-specific nanocarriers for delivery of platin into Her2-positive breast cancer cells (Sk-Br3) with strong therapeutic effects. The conjugate has a half-maximal inhibitory concentration (IC(50)) toward Sk-Br3 cells of 1.76 microg of Pt/mL, which is lower than that needed for cisplatin (3.5 microg/mL). The work demonstrates that the dumbbell-like Au-Fe(3)O(4) NPs are promising nanocarriers for highly sensitive diagnostic and therapeutic applications. | lld:pubmed |
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pubmed-article:19275156 | pubmed:language | eng | lld:pubmed |
pubmed-article:19275156 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19275156 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:19275156 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19275156 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19275156 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19275156 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19275156 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19275156 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:19275156 | pubmed:month | Apr | lld:pubmed |
pubmed-article:19275156 | pubmed:issn | 1520-5126 | lld:pubmed |
pubmed-article:19275156 | pubmed:author | pubmed-author:SunShouhengS | lld:pubmed |
pubmed-article:19275156 | pubmed:author | pubmed-author:XuChenjieC | lld:pubmed |
pubmed-article:19275156 | pubmed:author | pubmed-author:WangBaoduiB | lld:pubmed |
pubmed-article:19275156 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:19275156 | pubmed:day | 1 | lld:pubmed |
pubmed-article:19275156 | pubmed:volume | 131 | lld:pubmed |
pubmed-article:19275156 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:19275156 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:19275156 | pubmed:pagination | 4216-7 | lld:pubmed |
pubmed-article:19275156 | pubmed:dateRevised | 2010-9-22 | lld:pubmed |
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pubmed-article:19275156 | pubmed:year | 2009 | lld:pubmed |
pubmed-article:19275156 | pubmed:articleTitle | Dumbbell-like Au-Fe3O4 nanoparticles for target-specific platin delivery. | lld:pubmed |
pubmed-article:19275156 | pubmed:affiliation | Department of Chemistry, Brown University, Providence, Rhode Island 02912, USA. | lld:pubmed |
pubmed-article:19275156 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:19275156 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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