Linked Life Data

19273221

Source:http://linkedlifedata.com/resource/pubmed/id/19273221

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-3-10
pubmed:abstractText
The features of the enterohepatic circulation of bile acids in mammals are reviewed. Inputs into the circulating bile acids are primary bile acids synthesized from cholesterol in the hepatocyte and secondary bile acids formed by bacterial modification of primary bile acids in the distal intestine. Intestinal conservation of bile acids generates pools of individual bile acids whose relative sizes determine biliary bile acid composition. Efficient hepatic clearance results in low plasma bile acid levels, and virtually no renal excretion. Methods for characterizing the enterohepatic circulation are summarized. Bile acids have numerous physiological functions in the liver, biliary tract, and intestine resulting from their signaling and physicochemical properties.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1093-4715
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2584-98
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
The enterohepatic circulation of bile acids in mammals: form and functions.
pubmed:affiliation
Division of Gastroenterology. Department of Medicine, University of California, San Diego. La Jolla, California 92093-0063, USA. ahofmann@ucsd.edu
pubmed:publicationType
Journal Article, Review, Research Support, N.I.H., Extramural