Linked Life Data

19269415

Source:http://linkedlifedata.com/resource/pubmed/id/19269415

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-3-9
pubmed:abstractText
Quantum dots (QDs) have been used as a new class of bioprobes in medical imaging in recent years. The study of interaction between QDs and biomacromolecules is important for interpreting biological data. In this work, Rayleigh light scattering (RLS) was employed to investigate the nonspecific interaction between mercaptoacetic acid modified CdSe/ZnS quantum dots (MAA-QDs) and human immunoglobulin G (IgG). The conjugation processes between QDs and IgG in different conditions including addition sequence, pH were carefully studied. The addition of IgG to QDs solution was found to form a fixed size of QDs-IgG conjugate, with the QDs-to-IgG ratio of approximately 13, while the addition of QDs to IgG solution resulted in a gradually increased conjugate size, with variable QDs-to-IgG ratio till the binding saturation was reached.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1873-3573
pubmed:author
pubmed:issnType
Electronic
pubmed:day
15
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
700-4
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Investigation of the nonspecific interaction between quantum dots and immunoglobulin G using Rayleigh light scattering.
pubmed:affiliation
College of Chemistry and Molecular Sciences and State Key Laboratory of Virology, Wuhan University, Luojiashan, Wuhan 430072, Hubei, PR China.
pubmed:publicationType
Journal Article