|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0005516,
umls-concept:C0006142,
umls-concept:C0007806,
umls-concept:C0012634,
umls-concept:C0025202,
umls-concept:C0030705,
umls-concept:C0078058,
umls-concept:C0162597,
umls-concept:C0242379,
umls-concept:C0441889,
umls-concept:C0678226,
umls-concept:C0684249,
umls-concept:C1171892,
umls-concept:C1441547,
umls-concept:C1521761,
umls-concept:C1704231
|
|
pubmed:issue |
2
|
|
pubmed:dateCreated |
2009-8-11
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|
pubmed:abstractText |
Breast cancer, lung cancer and melanoma metastasize to the meninges in 5-15% of patients. The identification of specific biomarkers of disease may allow for earlier diagnosis and treatment. Preclinical evidence suggests the possible relevance of SDF-1 and VEGF in the homing and neoangiogenesis of metastases. We chose to measure these molecules in the cerebrospinal fluid (CSF) of melanoma, breast, and lung cancer patients being evaluated for neoplastic meningitis (NM).
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
1573-7373
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|
pubmed:author |
|
|
pubmed:issnType |
Electronic
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pubmed:volume |
94
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
229-34
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pubmed:meshHeading |
pubmed-meshheading:19267183-Adult,
pubmed-meshheading:19267183-Aged,
pubmed-meshheading:19267183-Breast Neoplasms,
pubmed-meshheading:19267183-Chemokine CXCL12,
pubmed-meshheading:19267183-Female,
pubmed-meshheading:19267183-Humans,
pubmed-meshheading:19267183-Lung Neoplasms,
pubmed-meshheading:19267183-Male,
pubmed-meshheading:19267183-Melanoma,
pubmed-meshheading:19267183-Meningitis,
pubmed-meshheading:19267183-Middle Aged,
pubmed-meshheading:19267183-Neoplasm Recurrence, Local,
pubmed-meshheading:19267183-Neoplasm Staging,
pubmed-meshheading:19267183-Prognosis,
pubmed-meshheading:19267183-Sensitivity and Specificity,
pubmed-meshheading:19267183-Tumor Markers, Biological,
pubmed-meshheading:19267183-Vascular Endothelial Growth Factor A
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|
pubmed:year |
2009
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pubmed:articleTitle |
Biomarkers of disease: cerebrospinal fluid vascular endothelial growth factor (VEGF) and stromal cell derived factor (SDF)-1 levels in patients with neoplastic meningitis (NM) due to breast cancer, lung cancer and melanoma.
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pubmed:affiliation |
Departments of Neuro-Oncology, The Brain Tumor Center, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. mgroves@mdanderson.org.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
