pubmed-article:19262119 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:19262119 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:19262119 | lifeskim:mentions | umls-concept:C0033572 | lld:lifeskim |
pubmed-article:19262119 | lifeskim:mentions | umls-concept:C1622501 | lld:lifeskim |
pubmed-article:19262119 | lifeskim:mentions | umls-concept:C1512505 | lld:lifeskim |
pubmed-article:19262119 | lifeskim:mentions | umls-concept:C0547047 | lld:lifeskim |
pubmed-article:19262119 | lifeskim:mentions | umls-concept:C0053163 | lld:lifeskim |
pubmed-article:19262119 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:19262119 | pubmed:dateCreated | 2009-3-5 | lld:pubmed |
pubmed-article:19262119 | pubmed:abstractText | We compared the in vitro effect of boric acid (BA) versus phenylboronic acid (PBA) on the migration of prostate and breast cancer cell lines and non-tumorigenic cells from the same tissues. Treatment at 24 hours with BA (< or =500 microM) did not inhibit chemotaxis on fibronectin in any cell line. However, treatment over the same time course with concentrations of PBA as low as 1 muM significantly inhibited cancer cell migration without effecting non-tumorigenic cell lines. The compounds did not affect cell adhesion or viability at 24 hours but did alter morphology; both decreased cancer cell viability at eight days. These results suggest that PBA is more potent than BA in targeting the metastatic and proliferative properties of cancer cells. | lld:pubmed |
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pubmed-article:19262119 | pubmed:language | eng | lld:pubmed |
pubmed-article:19262119 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:19262119 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:19262119 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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pubmed-article:19262119 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:19262119 | pubmed:issn | 1933-6926 | lld:pubmed |
pubmed-article:19262119 | pubmed:author | pubmed-author:PlopperGeorge... | lld:pubmed |
pubmed-article:19262119 | pubmed:author | pubmed-author:CarperStephen... | lld:pubmed |
pubmed-article:19262119 | pubmed:author | pubmed-author:HallCaseyC | lld:pubmed |
pubmed-article:19262119 | pubmed:author | pubmed-author:BradkeTiffany... | lld:pubmed |
pubmed-article:19262119 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:19262119 | pubmed:volume | 2 | lld:pubmed |
pubmed-article:19262119 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:19262119 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:19262119 | pubmed:pagination | 153-60 | lld:pubmed |
pubmed-article:19262119 | pubmed:dateRevised | 2010-12-7 | lld:pubmed |
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pubmed-article:19262119 | pubmed:articleTitle | Phenylboronic acid selectively inhibits human prostate and breast cancer cell migration and decreases viability. | lld:pubmed |
pubmed-article:19262119 | pubmed:affiliation | Department of Biology, Rensselaer Polytechnic Institute, Troy, New York 12180-3596, USA. | lld:pubmed |
pubmed-article:19262119 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:19262119 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
pubmed-article:19262119 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |