|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0001554,
umls-concept:C0021368,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0039005,
umls-concept:C0070166,
umls-concept:C0085828,
umls-concept:C0175677,
umls-concept:C0205082,
umls-concept:C0392756,
umls-concept:C0443252,
umls-concept:C0521447,
umls-concept:C1514485,
umls-concept:C1522318,
umls-concept:C1879547
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|
pubmed:issue |
3
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|
pubmed:dateCreated |
2009-3-5
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|
pubmed:abstractText |
The optimal duration of clopidogrel treatment following percutaneous coronary intervention (PCI) and the patient population that would benefit most are still unknown. In a porcine coronary injury model, we tested two different durations of clopidogrel treatment on severely or moderately injured arteries and examined the arterial response to injury. To understand the molecular mechanism, we also investigated the effects on transcription factors nuclear factor-kappaB (NF-kappaB) and activator protein 1 (AP-1).
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1365-2362
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pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
174-82
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pubmed:meshHeading |
pubmed-meshheading:19260946-Animals,
pubmed-meshheading:19260946-Aspirin,
pubmed-meshheading:19260946-Coronary Restenosis,
pubmed-meshheading:19260946-Disease Models, Animal,
pubmed-meshheading:19260946-Drug Therapy, Combination,
pubmed-meshheading:19260946-NF-kappa B,
pubmed-meshheading:19260946-Platelet Aggregation Inhibitors,
pubmed-meshheading:19260946-Statistics as Topic,
pubmed-meshheading:19260946-Sus scrofa,
pubmed-meshheading:19260946-Ticlopidine,
pubmed-meshheading:19260946-Time Factors,
pubmed-meshheading:19260946-Transcription Factor AP-1
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|
pubmed:year |
2009
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|
pubmed:articleTitle |
Long-term clopidogrel administration following severe coronary injury reduces proliferation and inflammation via inhibition of nuclear factor-kappaB and activator protein 1 activation in pigs.
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pubmed:affiliation |
Charité- Campus Benjamin Franklin, Berlin, Germany. klaus.pels@charite.de
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pubmed:publicationType |
Journal Article
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