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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
88
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pubmed:dateCreated |
2009-3-5
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pubmed:abstractText |
Recent research has proposed a role for HBV pre-S mutation in the development of HCC. Although the mechanism is not clear, pre-S mutant-induced endoplasmic reticulum (ER) stress and oxidative DNA damage may participate in this process. Therefore, we investigated the correlation of HBV pre-S mutation with ER stress and cellular oxidative DNA damage in HBV-related HCC patients.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0172-6390
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
55
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2028-32
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pubmed:meshHeading |
pubmed-meshheading:19260471-Aged,
pubmed-meshheading:19260471-Carcinoma, Hepatocellular,
pubmed-meshheading:19260471-DNA Damage,
pubmed-meshheading:19260471-DNA Glycosylases,
pubmed-meshheading:19260471-Endoplasmic Reticulum,
pubmed-meshheading:19260471-Female,
pubmed-meshheading:19260471-Hepatitis B Surface Antigens,
pubmed-meshheading:19260471-Hepatitis B virus,
pubmed-meshheading:19260471-Humans,
pubmed-meshheading:19260471-Immunohistochemistry,
pubmed-meshheading:19260471-Liver,
pubmed-meshheading:19260471-Liver Neoplasms,
pubmed-meshheading:19260471-Male,
pubmed-meshheading:19260471-Middle Aged,
pubmed-meshheading:19260471-Mutation,
pubmed-meshheading:19260471-Oxidative Stress,
pubmed-meshheading:19260471-Protein Precursors,
pubmed-meshheading:19260471-Viral Envelope Proteins
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pubmed:articleTitle |
The correlation of hepatitis B virus pre-S mutation with cellular oxidative DNA damage in hepatocellular carcinoma.
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pubmed:affiliation |
Department of Medicine and Digestive Disease Research Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
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pubmed:publicationType |
Journal Article
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