Linked Life Data

19251781

Source:http://linkedlifedata.com/resource/pubmed/id/19251781

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2009-8-3
pubmed:abstractText
Urban air pollution has been associated with morbidity but little information exists on how it affects diurnal variation of lung function in children with asthma. The purpose of this study was to investigate the acute effects of traffic-related pollution on lung function among children with asthma. We recorded morning and evening forced expiratory volume in 1 s (FEV(1)) for 28 consecutive days in 182 elementary schoolchildren with physician-diagnosed asthma, and monitored ambient hourly air pollution concentrations. An interquartile range (IQR) increase (6.0 microg m(-3)) in the previous 24-h (20:00 h to 20:00 h) mean concentration of fine particulate matter 2.5 microm in diameter (PM(2.5)) was associated with a 0.54% (95% confidence interval (CI) 0.06-1.02) decrease in bedtime FEV(1) (p = 0.027). This association persisted in two-pollutant models with ozone, nitrogen dioxide and sulphur dioxide. An IQR increase in mean daytime (08:00 h to 20:00 h) PM(2.5) of 6.5 microg m(-3) was associated with a 0.73% (95% CI 0.10-1.37) decrease in FEV(1) over the course of the day expressed as 100 x (FEV(1) bedtime - FEV(1) morning)/FEV(1) morning (p = 0.024). This study suggests that, in children with asthma, relatively low concentrations of urban air pollution worsen lung function over a short period of time, even within a day. Of the pollutants measured, PM(2.5 )appears to be the most important.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1399-3003
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
316-23
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Acute effects of outdoor air pollution on forced expiratory volume in 1 s: a panel study of schoolchildren with asthma.
pubmed:affiliation
University of Ottawa, Ottawa, ON, Canada. rdales@ohri.ca
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't