Linked Life Data

19251577

Source:http://linkedlifedata.com/resource/pubmed/id/19251577

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2009-4-29
pubmed:abstractText
To avoid adverse reactions to allergenic ingredients, manufacturers recommend "sensitivity testing" prior to use of hair dyes. However, there is no standardised method and the recommendation is often not followed. We assessed the ability of a standardised test system from one manufacturer (Colourstart, a small skin surface water-slide transfer containing p-phenylenediamine (PPD)) for its ability to elicit a reaction in those with a previously diagnosed contact allergy to PPD, the main hair dye allergen. Thirty volunteers with diagnosed PPD allergy (10 each of 3+, 2+ and 1+) were assessed with the Colourstart system according to the manufacturer's instructions. Responses were recorded after 48h exposure. Colourstart identified 100% of those with a 3+ reaction to the diagnostic patch test, 80% of the 2+ reactors and just 10% of the 1+ reactors. Thus, Colourstart successfully identified those individuals with the greatest sensitivity to PPD, who might therefore be at risk of a severe reaction if they dyed their hair. It also identified 83% of those who reported a severe/very severe history of hair dye adverse reaction. However, its proper use and interpretation are necessary if those consumers most at risk are to have the information necessary to avoid serious adverse reactions to hair dyes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1167-1122
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
232-7
pubmed:meshHeading
pubmed:articleTitle
Pre-testing in hair dye users: an assessment of the Colourstart system.
pubmed:affiliation
DABMEB Consultancy, Sharnbrook, Bedfordshire, UK. david.basketter@ukonline.co.uk
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't