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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2009-3-2
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pubmed:abstractText |
Recent studies of the genetics of alcoholism have considered genetic factors in alcohol metabolism and have identified functional polymorphisms in genes encoding enzymes involved in ethanol metabolism. The aim of this study was to estimate the genotype and allele frequencies of polymorphisms of three major ethanol-metabolizing enzymes (ADH2, ALDH2 and CYP2E1) in Koreans and to compare them with those of other ethnic groups.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1365-2710
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
225-30
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pubmed:meshHeading |
pubmed-meshheading:19250143-Alcohol Dehydrogenase,
pubmed-meshheading:19250143-Aldehyde Dehydrogenase,
pubmed-meshheading:19250143-Central Nervous System Depressants,
pubmed-meshheading:19250143-Cytochrome P-450 CYP2E1,
pubmed-meshheading:19250143-DNA,
pubmed-meshheading:19250143-Databases, Genetic,
pubmed-meshheading:19250143-Ethanol,
pubmed-meshheading:19250143-Ethnic Groups,
pubmed-meshheading:19250143-Gene Frequency,
pubmed-meshheading:19250143-Genotype,
pubmed-meshheading:19250143-Humans,
pubmed-meshheading:19250143-Korea,
pubmed-meshheading:19250143-Polymorphism, Genetic,
pubmed-meshheading:19250143-Polymorphism, Single Nucleotide,
pubmed-meshheading:19250143-Reverse Transcriptase Polymerase Chain Reaction
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pubmed:year |
2009
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pubmed:articleTitle |
Comparison of genetic polymorphisms of CYP2E1, ADH2, and ALDH2 genes involved in alcohol metabolism in Koreans and four other ethnic groups.
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pubmed:affiliation |
Department of Pharmacological Research, National Institute of Toxicological Research, Korea Food and Drug Administration, Seoul, South Korea.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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