Linked Life Data

19250063

Source:http://linkedlifedata.com/resource/pubmed/id/19250063

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
2009-7-1
pubmed:abstractText
miRNAs (microRNAs) are a class of non-coding RNAs that inhibit gene expression by binding to recognition elements, mainly in the 3' UTR (untranslated region) of mRNA. A single miRNA can target several hundred mRNAs, leading to a complex metabolic network. miR-16 (miRNA-16), located on chromosome 13q14, is involved in cell proliferation and apoptosis regulation; it may interfere with either oncogenic or tumour suppressor pathways, and is implicated in leukaemogenesis. These data prompted us to search for and validate novel targets of miR-16.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
1768-322X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
101
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
511-24
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Two new miR-16 targets: caprin-1 and HMGA1, proteins implicated in cell proliferation.
pubmed:affiliation
LBMC, CNRS UMR5239, IFR128, Faculté de Médecine Lyon Sud, Université Lyon 1, Pierre Bénite, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't