Linked Life Data

19246847

Source:http://linkedlifedata.com/resource/pubmed/id/19246847

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2009-2-27
pubmed:abstractText
Earlier studies have demonstrated that an impaired capacity to increase heart rate (HR) and a slowed HR recovery following exercise are both associated with cardiovascular mortality. We sought to determine whether HR profiles during exercise testing are superior to respiratory gas parameters in predicting mortality among patients with cardiac disease. Five-hundred and fifty stable cardiac patients (63.4 +/- 9.9 years) underwent a symptom-limited incremental exercise test. Measurements included peak VO(2), VE/VCO(2) slope, HR increase (HR difference from rest to peak exercise), and HR recovery (HR difference from peak to 2 minutes after exercise). Twenty-eight cardiovascular-deaths occurred during 4 years of prospective follow-up. In multivariate analysis, the CPX parameters were found to be significant predictors of cardiovascular-death; peak VO(2) (relative risk (RR), 3.44; 95% CI 1.37 to 8.62; P = 0.008), VE/VCO(2) slope (RR, 1.52; 95% CI 1.11 to 2.08; P = 0.009), while HR increase and HR recovery were determined not to be independent predictors. Although HR profiles during exercise testing are easy to perform and useful as prognostic predictors in patients with cardiac disease, they are not superior to respiratory gas analysis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1349-2365
pubmed:author
pubmed:issnType
Print
pubmed:volume
50
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
59-71
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Prognostic value of heart rate profiles during cardiopulmonary exercise testing in patients with cardiac disease.
pubmed:affiliation
The Cardiovascular Institute, Tokyo Medical and Dental University, Tokyo, Japan.
pubmed:publicationType
Journal Article, Comparative Study