Linked Life Data

19244167

Source:http://linkedlifedata.com/resource/pubmed/id/19244167

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2009-3-4
pubmed:abstractText
Lynch syndrome is caused by inherited mutations in DNA mismatch repair genes (primarily MSH2, MLH1, MSH6, and PMS2) and is one of the most prevalent inherited cancer syndromes. Several models have been developed to predict the occurrence of Lynch syndrome in high-risk patients and families, but it is not known how these models compare with one another or how they perform for colorectal cancer patients from the general population. We used data from such patients to test the ability of four models--Leiden, MMRpredict, PREMM(1,2), and MMRpro--to distinguish between those who did and did not carry DNA mismatch repair gene mutations.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1460-2105
pubmed:author
pubmed:issnType
Electronic
pubmed:day
4
pubmed:volume
101
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
331-40
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Prediction of Lynch syndrome in consecutive patients with colorectal cancer.
pubmed:affiliation
Department of Genetics, Faculty of Medicine, Memorial University, St John's, Newfoundland, Canada A1B 3V6. rcgreen@mun.ca
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't