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pubmed-article:19243953pubmed:abstractTextBy combining the structural features of acridone based anti-cancer drugs (like amsacrine) and MDR modulator propafenone, acridones with hydroxyl amine chain at N-10 have been designed and synthesized. These molecules exhibit appreciable interactions with p-gp and Mg(2+) indicating their suitability to modulate p-gp mediated multi drug resistance.lld:pubmed
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pubmed-article:19243953pubmed:articleTitleSearch for MDR modulators: design, syntheses and evaluations of N-substituted acridones for interactions with p-glycoprotein and Mg2+.lld:pubmed
pubmed-article:19243953pubmed:affiliationDepartment of Chemistry, Guru Nanak Dev University, Amritsar 143 005, India. palwinder_singh_2000@yahoo.comlld:pubmed
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