| pubmed-article:19243901 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19243901 | lifeskim:mentions | umls-concept:C0020517 | lld:lifeskim |
| pubmed-article:19243901 | lifeskim:mentions | umls-concept:C2720270 | lld:lifeskim |
| pubmed-article:19243901 | lifeskim:mentions | umls-concept:C0663655 | lld:lifeskim |
| pubmed-article:19243901 | lifeskim:mentions | umls-concept:C2926612 | lld:lifeskim |
| pubmed-article:19243901 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:19243901 | pubmed:dateCreated | 2010-12-6 | lld:pubmed |
| pubmed-article:19243901 | pubmed:abstractText | A potentially life-threatening hypersensitive reaction occurs in association with initiation of HIV nucleoside analogue abacavir therapy in 4 to 8% of patients. Preliminary studies appear to confirm the role of the immune system in abacavir hypersensitivity. The reaction is possibly the result of presentation of drug peptides onto HLA, that may induce a pathogenic T-cell response. Hypersensitivity reaction to abacavir is strongly associated with the presence of the HLA-B*5701 allele and prospective HLA-B*5701 genetic screening has now been instituted in clinical practice to reduce the risk of hypersensitivity reaction. | lld:pubmed |
| pubmed-article:19243901 | pubmed:language | fre | lld:pubmed |
| pubmed-article:19243901 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243901 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19243901 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243901 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243901 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243901 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243901 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243901 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243901 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243901 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19243901 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:19243901 | pubmed:issn | 1768-3114 | lld:pubmed |
| pubmed-article:19243901 | pubmed:author | pubmed-author:LeclercqEE | lld:pubmed |
| pubmed-article:19243901 | pubmed:author | pubmed-author:CeppaFF | lld:pubmed |
| pubmed-article:19243901 | pubmed:author | pubmed-author:DelacourHH | lld:pubmed |
| pubmed-article:19243901 | pubmed:author | pubmed-author:ServonnetAA | lld:pubmed |
| pubmed-article:19243901 | pubmed:copyrightInfo | Copyright © 2009 Elsevier Masson SAS. All rights reserved. | lld:pubmed |
| pubmed-article:19243901 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19243901 | pubmed:volume | 58 | lld:pubmed |
| pubmed-article:19243901 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19243901 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19243901 | pubmed:pagination | e95-100 | lld:pubmed |
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| pubmed-article:19243901 | pubmed:meshHeading | pubmed-meshheading:19243901... | lld:pubmed |
| pubmed-article:19243901 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:19243901 | pubmed:articleTitle | [HLA-B*5701 and abacavir hypersensitivity reaction]. | lld:pubmed |
| pubmed-article:19243901 | pubmed:affiliation | Laboratoire de biochimie, hôpital d'instruction des armées Bégin, 69, avenue de Paris, 94163 Saint-Mandé cedex, France. a_servonnet@yahoo.fr | lld:pubmed |
| pubmed-article:19243901 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19243901 | pubmed:publicationType | English Abstract | lld:pubmed |
| entrez-gene:3106 | entrezgene:pubmed | pubmed-article:19243901 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:19243901 | lld:entrezgene |
