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rdf:type |
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lifeskim:mentions |
umls-concept:C0011860,
umls-concept:C0015663,
umls-concept:C0202042,
umls-concept:C0205214,
umls-concept:C0205419,
umls-concept:C0237401,
umls-concept:C0332281,
umls-concept:C0332307,
umls-concept:C0679058,
umls-concept:C0814942,
umls-concept:C1442506,
umls-concept:C1547699,
umls-concept:C2700640
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pubmed:issue |
5
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pubmed:dateCreated |
2009-4-6
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pubmed:abstractText |
Recently, three groups independently reported that variation in MTNR1B, the gene encoding melatonin receptor 1B, was associated with an increased risk of type 2 diabetes, increased fasting plasma glucose and impaired insulin secretion in populations of European ancestry. In the present study, we investigated whether a single MTNR1B polymorphism was associated with type 2 diabetes in Han Chinese individuals, to elucidate whether this is a cross-populational effect.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1432-0428
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
830-3
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pubmed:meshHeading |
pubmed-meshheading:19241057-Aged,
pubmed-meshheading:19241057-Asian Continental Ancestry Group,
pubmed-meshheading:19241057-Blood Glucose,
pubmed-meshheading:19241057-Body Mass Index,
pubmed-meshheading:19241057-China,
pubmed-meshheading:19241057-DNA,
pubmed-meshheading:19241057-Diabetes Mellitus, Type 2,
pubmed-meshheading:19241057-Fasting,
pubmed-meshheading:19241057-Female,
pubmed-meshheading:19241057-Genetic Variation,
pubmed-meshheading:19241057-Humans,
pubmed-meshheading:19241057-Male,
pubmed-meshheading:19241057-Middle Aged,
pubmed-meshheading:19241057-Polymorphism, Genetic,
pubmed-meshheading:19241057-Receptor, Melatonin, MT2,
pubmed-meshheading:19241057-Reference Values,
pubmed-meshheading:19241057-Regression Analysis,
pubmed-meshheading:19241057-Risk Factors,
pubmed-meshheading:19241057-Urban Population
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pubmed:year |
2009
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pubmed:articleTitle |
A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals.
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pubmed:affiliation |
Department of Clinical Sciences, CRC Malmö University Hospital, Lund University Diabetes Center, Malmö, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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