Linked Life Data

19239645

Source:http://linkedlifedata.com/resource/pubmed/id/19239645

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2009-2-25
pubmed:abstractText
Ceragenin CSA-13 is a bile-acid-based mimic of endogenous antimicrobial peptides and shares a mechanism of action with many of these antimicrobial agents. Because CSA-13 is not peptide based, it is not a substrate for the proteases that are found in the oral cavity, which are capable of degrading antimicrobial peptides. Furthermore, the simplicity of the ceragenins makes them easier to prepare and purify than antimicrobial peptides. In this study, we examined the antimicrobial activities of CSA-13 against oral pathogens and found that this compound was bactericidal against all of the strains tested.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1399-302X
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
24
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
170-2
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Ceragenin CSA-13 exhibits antimicrobial activity against cariogenic and periodontopathic bacteria.
pubmed:affiliation
Department of Disease Control and Molecular Epidemiology, Health Sciences University of Hokkaido, Hokkaido, Japan. emiko@hoku-iryo-u.ac.jp
pubmed:publicationType
Journal Article, Comparative Study