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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2009-3-11
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pubmed:abstractText |
Expert-based genotypic interpretation systems are standard methods for guiding treatment selection for patients infected with human immunodeficiency virus type 1. We previously introduced the software pipeline geno2pheno-THEO (g2p-THEO), which on the basis of viral sequence predicts the response to treatment with a combination of antiretroviral compounds by applying methods from statistical learning and the estimated potential of the virus to escape from drug pressure.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0022-1899
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pubmed:author |
pubmed-author:AltmannAndréA,
pubmed-author:BüchJoachimJ,
pubmed-author:BeerenwinkelNikoN,
pubmed-author:DäumerMartinM,
pubmed-author:FesselW JeffreyWJ,
pubmed-author:KaiserRolfR,
pubmed-author:LengauerThomasT,
pubmed-author:PeresYardenaY,
pubmed-author:RheeSoo-YonSY,
pubmed-author:SönnerborgAndersA,
pubmed-author:SchülterEugenE,
pubmed-author:ShaferRobert WRW,
pubmed-author:ZazziMaurizioM
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
199
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
999-1006
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pubmed:dateRevised |
2009-6-8
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pubmed:meshHeading |
pubmed-meshheading:19239365-Anti-HIV Agents,
pubmed-meshheading:19239365-Decision Support Systems, Clinical,
pubmed-meshheading:19239365-Drug Therapy, Combination,
pubmed-meshheading:19239365-Genetic Predisposition to Disease,
pubmed-meshheading:19239365-Genotype,
pubmed-meshheading:19239365-HIV Infections,
pubmed-meshheading:19239365-HIV-1,
pubmed-meshheading:19239365-Humans,
pubmed-meshheading:19239365-Predictive Value of Tests,
pubmed-meshheading:19239365-ROC Curve,
pubmed-meshheading:19239365-Reproducibility of Results,
pubmed-meshheading:19239365-Retrospective Studies,
pubmed-meshheading:19239365-Software
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pubmed:year |
2009
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pubmed:articleTitle |
Predicting the response to combination antiretroviral therapy: retrospective validation of geno2pheno-THEO on a large clinical database.
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pubmed:affiliation |
Max Planck Institute for Informatics, Saarbrücken, University of Cologne, Cologne, Germany. altmann@mpi-inf.mpg.de
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Validation Studies
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