Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
36
pubmed:dateCreated
1991-11-7
pubmed:abstractText
The production of different cytokines, namely interleukin-2, interleukin-1 and tumor necrosis factor-alpha produced by peripheral immunocompetent cells was evaluated in patients with systemic lupus erythematosus in active and inactive stage of the disease. The results obtained were compared to healthy controls. It has been found that lymphocytes from both groups of SLE patients produced similarly less interleukin-2 activity. Interleukin-1 activity of monocytes was significantly reduced only in patients with active stage of the disease, whereas tumor necrosis factor-alpha production was diminished even in cases of inactive SLE. The simultaneous detection of the above mentioned cytokines may indicate further details concerning immunoregulatory disturbances of systemic lupus erythematosus.
pubmed:commentsCorrections
pubmed:language
hun
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0030-6002
pubmed:author
pubmed:issnType
Print
pubmed:day
8
pubmed:volume
132
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1971-4
pubmed:dateRevised
2009-10-21
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
[Cytokine production in patients with systemic lupus erythematosus].
pubmed:affiliation
Semmelweis Orvostudományi Egyetem, Budapest, II. Belgyógyászati Klinika.
pubmed:publicationType
Journal Article, English Abstract, Review