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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2009-5-27
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pubmed:abstractText |
Herpes simplex virus-type 2 (HSV-2) can cause acute retinal necrosis (ARN), which can lead to exudative and rhegmatogenous retinal detachment, yet little is known about the cellular and molecular mechanisms of HSV-2 entry into retinal pigment epithelial (RPE) cells. The goal of this study was to establish the identity of the critical receptors used by the virus for infection.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cell Adhesion Molecules,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Glycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/PILRA protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Immunologic,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Tumor Necrosis Factor...,
http://linkedlifedata.com/resource/pubmed/chemical/TNFRSF14 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/nectins
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1552-5783
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
50
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2878-87
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:19234349-Animals,
pubmed-meshheading:19234349-Blotting, Western,
pubmed-meshheading:19234349-Cell Adhesion Molecules,
pubmed-meshheading:19234349-Cercopithecus aethiops,
pubmed-meshheading:19234349-Down-Regulation,
pubmed-meshheading:19234349-Flow Cytometry,
pubmed-meshheading:19234349-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:19234349-Gene Silencing,
pubmed-meshheading:19234349-Herpesvirus 2, Human,
pubmed-meshheading:19234349-Humans,
pubmed-meshheading:19234349-Membrane Glycoproteins,
pubmed-meshheading:19234349-RNA, Small Interfering,
pubmed-meshheading:19234349-Receptors, Immunologic,
pubmed-meshheading:19234349-Receptors, Tumor Necrosis Factor, Member 14,
pubmed-meshheading:19234349-Retinal Pigment Epithelium,
pubmed-meshheading:19234349-Vero Cells,
pubmed-meshheading:19234349-Viral Plaque Assay,
pubmed-meshheading:19234349-Virus Replication
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pubmed:year |
2009
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pubmed:articleTitle |
Role of nectin-1, HVEM, and PILR-alpha in HSV-2 entry into human retinal pigment epithelial cells.
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pubmed:affiliation |
Departments of Ophthalmology and Visual Sciences, College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, USA. dshukla@uic.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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