Linked Life Data

19231307

Source:http://linkedlifedata.com/resource/pubmed/id/19231307

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-6-5
pubmed:abstractText
Listeria monocytogenes, a small, facultative anaerobic, Gram-positive motile bacillus, is an important cause of foodborne illness which disproportionately affects pregnant women and their newborns. Listeria infects many types of animals and contaminates numerous foods including vegetables, milk, chicken and beef. This organism has a unique proclivity to infect the fetoplacental unit with the ability to invade cells, multiply intracellularly and be transmitted cell-to-cell. The organism possesses several virulence factors, including internalin A and internalin B, which facilitate the direct invasion of cells. Cell-to-cell transmission is promoted by the bacterial surface protein ActA which is regulated by a transcriptional activator known as positive regulatory factor A. Both innate and adaptive immune responses enable the host to eliminate this pathogen. Clinical manifestations of infection in the newborn fall into the traditional categories of early- and late-onset sepsis. Therapeutic recommendations include ampicillin and gentamicin for 14-21 days.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
1878-0946
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
14
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
228-33
pubmed:dateRevised
2010-11-18
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Listeriosis.
pubmed:affiliation
Department of Pediatrics, Children's Hospital of Geneva, University Hospitals of Geneva, 6 rue Willy-Donzé, 1211 Geneva 14, Switzerland. Klara.PosfayBarbe@hcuge.ch
pubmed:publicationType
Journal Article, Review