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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15
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pubmed:dateCreated |
2009-3-31
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pubmed:abstractText |
Mild mannered! A highly diastereo- and enantioselective Mannich-type reaction of glycine Schiff base 1 has been developed by using the N,N'-dioxide L-Cu(II) complex as a catalyst. Various optically active anti-alpha,beta-diamino acid esters were obtained in good yields with up to 96:4 d.r. and 97% ee. This straightforward method features a low catalyst loading and mild reaction conditions.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1521-3765
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
15
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3678-81
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pubmed:dateRevised |
2009-8-4
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pubmed:meshHeading |
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pubmed:year |
2009
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pubmed:articleTitle |
A N,N'-dioxide-copper(II) complex as an efficient catalyst for the enantioselective and diastereoselective Mannich-type reaction of glycine Schiff bases with aldimines.
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pubmed:affiliation |
Key Laboratory of Green Chemistry & Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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