|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0007586,
umls-concept:C0205531,
umls-concept:C0205618,
umls-concept:C0226896,
umls-concept:C0238301,
umls-concept:C0442027,
umls-concept:C1280500,
umls-concept:C1521801,
umls-concept:C1527415,
umls-concept:C1609861,
umls-concept:C1709060,
umls-concept:C1709518
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2009-2-20
|
|
pubmed:abstractText |
Cell cycle dysregulation resulting in expression of antiapoptotic genes and uncontrolled proliferation is a feature of undifferentiated nasopharyngeal carcinoma. The pharmacodynamic effects of seliciclib, a cyclin-dependent kinase (CDK) inhibitor, were studied in patients with nasopharyngeal carcinoma.
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|
pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Feb
|
|
pubmed:issn |
1078-0432
|
|
pubmed:author |
pubmed-author:ChiaoJudyJ,
pubmed-author:CuiChun-YingCY,
pubmed-author:DongDifengD,
pubmed-author:GohBoon-CherBC,
pubmed-author:GreenSimonS,
pubmed-author:HsiehWen-SonWS,
pubmed-author:LaiYoke-FongYF,
pubmed-author:LeeSoo-ChinSC,
pubmed-author:LohThomasT,
pubmed-author:MowBenjaminB,
pubmed-author:PehBee-KeowBK,
pubmed-author:Salto-TellezManuelM,
pubmed-author:SohDonnyD,
pubmed-author:SooRossR,
pubmed-author:SoongRichieR,
pubmed-author:WongLim-SoonLS
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
15
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1435-42
|
|
pubmed:meshHeading |
pubmed-meshheading:19228744-Administration, Oral,
pubmed-meshheading:19228744-Adult,
pubmed-meshheading:19228744-Aged,
pubmed-meshheading:19228744-Antineoplastic Agents,
pubmed-meshheading:19228744-Apoptosis,
pubmed-meshheading:19228744-Cell Cycle,
pubmed-meshheading:19228744-Cyclin D1,
pubmed-meshheading:19228744-DNA, Viral,
pubmed-meshheading:19228744-Female,
pubmed-meshheading:19228744-Gene Expression Profiling,
pubmed-meshheading:19228744-Humans,
pubmed-meshheading:19228744-Immunohistochemistry,
pubmed-meshheading:19228744-Male,
pubmed-meshheading:19228744-Middle Aged,
pubmed-meshheading:19228744-Nasopharyngeal Neoplasms,
pubmed-meshheading:19228744-Proto-Oncogene Proteins c-bcl-2,
pubmed-meshheading:19228744-Purines
|
|
pubmed:year |
2009
|
|
pubmed:articleTitle |
Pharmacodynamic effects of seliciclib, an orally administered cell cycle modulator, in undifferentiated nasopharyngeal cancer.
|
|
pubmed:affiliation |
Department of Hematology-Oncology, National University Hospital, Oncology Research Institute, School of Computing, and Department of Head and Neck Surgery, National University of Singapore, Singapore.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
