rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2009-2-20
|
pubmed:abstractText |
The proteasome inhibitor bortezomib inhibited cell growth and angiogenesis in neuroblastoma. Bortezomib has been shown to induce synergistic activity when combined with other antineoplastic agents. Here we have investigated the antitumor activity of bortezomib in combination with fenretinide, a synthetic retinoid, against neuroblastoma cells.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
1078-0432
|
pubmed:author |
pubmed-author:BrignoleChiaraC,
pubmed-author:CarosioRobertaR,
pubmed-author:CilliMicheleM,
pubmed-author:Di PaoloDanielaD,
pubmed-author:GaliettaLuis J VLJ,
pubmed-author:LoiMonicaM,
pubmed-author:MarimpietriDaniloD,
pubmed-author:NicoBeatriceB,
pubmed-author:PagnanGabriellaG,
pubmed-author:PastorinoFabioF,
pubmed-author:PezzoloAnnalisaA,
pubmed-author:PiccardiFedericaF,
pubmed-author:PistoiaVitoV,
pubmed-author:PonzoniMircoM,
pubmed-author:RibattiDomenicoD
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
15
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1199-209
|
pubmed:meshHeading |
pubmed-meshheading:19228726-Animals,
pubmed-meshheading:19228726-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:19228726-Apoptosis,
pubmed-meshheading:19228726-Boronic Acids,
pubmed-meshheading:19228726-Cell Line, Tumor,
pubmed-meshheading:19228726-Cell Proliferation,
pubmed-meshheading:19228726-Chick Embryo,
pubmed-meshheading:19228726-Endoplasmic Reticulum,
pubmed-meshheading:19228726-Fenretinide,
pubmed-meshheading:19228726-Humans,
pubmed-meshheading:19228726-Mice,
pubmed-meshheading:19228726-Neuroblastoma,
pubmed-meshheading:19228726-Pyrazines,
pubmed-meshheading:19228726-Xenograft Model Antitumor Assays
|
pubmed:year |
2009
|
pubmed:articleTitle |
The combined therapeutic effects of bortezomib and fenretinide on neuroblastoma cells involve endoplasmic reticulum stress response.
|
pubmed:affiliation |
Laboratory of Oncology, G. Gaslini Children's Hospital, Genoa, Italy. gabriellapagnan@ospedale-gaslini.ge
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|