Linked Life Data

19225706

Source:http://linkedlifedata.com/resource/pubmed/id/19225706

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2009-5-13
pubmed:abstractText
Churg-Strauss syndrome (CSS) is a rare multisystem autoimmune disease characterized by diffuse eosinophilic infiltration and necrotizing vasculitis. There are typical manifestations of longstanding rhinosinusitis and polyposis but otological manifestations are rare and characterized by dense aural discharge, granulomatous eosinophilic infiltrate in the mastoid and middle ear with conductive hearing loss, and progressive sensory neural hearing loss--all of which are not responsive to conventional treatment. We describe the case of a 59-year-old man with a rare presentation of CSS that included chronic bilateral otitis media with hearing loss and life-threatening pericardial tamponade. Treatment with pericardiocentesis, prednisone and cyclophosphamide was beneficial and resulted in an improvement of the pericardial and otological manifestations. Early recognition and treatment of otological involvement in CSS is extremely important because of the dramatic response to corticosteroids which may prevent progression of hearing loss.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
1434-9949
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
28 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S35-8
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Churg-Strauss syndrome: a rare presentation with otological and pericardial manifestations: case report and review of the literature.
pubmed:affiliation
Department of Medicine C, Sackler Faculty of Medicine, Tel-Aviv University, Wolfson Medical Center, Halochamim 62, Holon, Israel, 58100.
pubmed:publicationType
Journal Article, Review, Case Reports