Source:http://linkedlifedata.com/resource/pubmed/id/19225263
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2009-2-19
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pubmed:abstractText |
The extracellular matrix (ECM) undergoes constant dynamic changes; proteolytic enzymes, particularly the serine proteases plasmin, trypsin and elastase, catalyze critical functions in these processes. Notably, ECM degradation disorders have been reported in various morbid conditions, including cardiac infarction, atheromatosis, and neoplastic diseases, indicating a physiological requirement for proper ECM maintenance. Here we define the role of proteolytic enzymes in the development of aging by assessing changes in proteolytic enzyme activity in serum during aging in rats.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1594-0667
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
9-13
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:19225263-Aging,
pubmed-meshheading:19225263-Animals,
pubmed-meshheading:19225263-Fibrinolysin,
pubmed-meshheading:19225263-Male,
pubmed-meshheading:19225263-Pancreatic Elastase,
pubmed-meshheading:19225263-Peptide Hydrolases,
pubmed-meshheading:19225263-Rats,
pubmed-meshheading:19225263-Rats, Wistar,
pubmed-meshheading:19225263-Trypsin
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pubmed:year |
2009
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pubmed:articleTitle |
Proteolytic enzyme activity as a result of aging.
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pubmed:affiliation |
Department of Immunology, Transplant Medicine and Internal Diseases, Medical University of Warsaw, Transplantation Institute, 02-006 Warsaw, Poland. leszekpaczek@onet.pl
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pubmed:publicationType |
Journal Article
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