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pubmed:abstractText |
To evaluate the capability of P947, a magnetic resonance (MR) imaging contrast agent that molecularly targets matrix metalloproteinases (MMPs), to aid detection and imaging of MMPs in atherosclerotic lesions in vivo; its specificity compared with that of P1135; expression and distribution of MMPs in atherosclerotic vessels; and in vivo distribution and molecular localization of fluorescent europium (Eu) P947.
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pubmed:affiliation |
Translational and Molecular Imaging Institute, Department of Radiology, Zena and Michael A. Wiener Cardiovascular Institute, Mount Sinai Schoolof Medicine, New York, NY 10029, USA.
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