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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
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pubmed:dateCreated |
1991-11-4
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pubmed:abstractText |
Three subpopulations of light chains in Xenopus can be distinguished by monoclonal antibodies as well as by electrophoretic mobility on SDS-PAGE, peptide map and cell surface distribution. Analysis of these proteins from LPS-stimulated lymphocytes culture supernatants by two-dimensional gel electrophoresis showed a heterogeneity comparable to that observed for mouse kappa light chains. However, evidence from the selective expression of light chain subpopulations, as well as highly restricted light chain representation in anti-DNP antibodies, supports earlier findings that an antibody response in Xenopus is greatly limited in heterogeneity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
pubmed:issn |
0161-5890
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
985-94
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1922112-Animals,
pubmed-meshheading:1922112-Antibodies, Monoclonal,
pubmed-meshheading:1922112-Antibody Diversity,
pubmed-meshheading:1922112-Antibody Specificity,
pubmed-meshheading:1922112-Blotting, Western,
pubmed-meshheading:1922112-Electrophoresis, Gel, Two-Dimensional,
pubmed-meshheading:1922112-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:1922112-Flow Cytometry,
pubmed-meshheading:1922112-Immunoglobulin Light Chains,
pubmed-meshheading:1922112-Intestines,
pubmed-meshheading:1922112-Spleen,
pubmed-meshheading:1922112-Thymus Gland,
pubmed-meshheading:1922112-Xenopus laevis
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pubmed:year |
1991
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pubmed:articleTitle |
Light chain heterogeneity in the amphibian Xenopus.
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pubmed:affiliation |
Basel Institute for Immunology, Switzerland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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