Source:http://linkedlifedata.com/resource/pubmed/id/19218333
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2009-3-30
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pubmed:abstractText |
In late-stage chronic heart failure (CHF), elevated cytokines and cachexia are often observed. Several studies have shown that exercise training exerts beneficial effects on skeletal muscle in this setting. Furthermore, it has been shown that the expression of myostatin, a key regulator of skeletal muscle mass, is increased in a variety of cachectic states. This study aimed to investigate the expression of myostatin in CHF, the influence of exercise training on myostatin levels, and regulation of myostatin by tumour necrosis factor-alpha (TNF-alpha).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1388-9842
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
11
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
342-8
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pubmed:dateRevised |
2011-6-8
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pubmed:meshHeading |
pubmed-meshheading:19218333-Animals,
pubmed-meshheading:19218333-Cells, Cultured,
pubmed-meshheading:19218333-Disease Models, Animal,
pubmed-meshheading:19218333-Electrophoresis, Polyacrylamide Gel,
pubmed-meshheading:19218333-Exercise Therapy,
pubmed-meshheading:19218333-Gene Expression,
pubmed-meshheading:19218333-Heart Failure,
pubmed-meshheading:19218333-Muscle, Skeletal,
pubmed-meshheading:19218333-Myocardium,
pubmed-meshheading:19218333-Myostatin,
pubmed-meshheading:19218333-RNA,
pubmed-meshheading:19218333-Rats,
pubmed-meshheading:19218333-Rats, Inbred WKY,
pubmed-meshheading:19218333-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:19218333-Tumor Necrosis Factor-alpha
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pubmed:year |
2009
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pubmed:articleTitle |
Impact of exercise training on myostatin expression in the myocardium and skeletal muscle in a chronic heart failure model.
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pubmed:affiliation |
Clinic of Cardiology, University Leipzig-Heart Center Leipzig, Strümpellstrasse 39, D-04289 Leipzig, Germany. karsten.lenk@med.uni-leipzig.de
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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