Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2009-3-30
pubmed:abstractText
In late-stage chronic heart failure (CHF), elevated cytokines and cachexia are often observed. Several studies have shown that exercise training exerts beneficial effects on skeletal muscle in this setting. Furthermore, it has been shown that the expression of myostatin, a key regulator of skeletal muscle mass, is increased in a variety of cachectic states. This study aimed to investigate the expression of myostatin in CHF, the influence of exercise training on myostatin levels, and regulation of myostatin by tumour necrosis factor-alpha (TNF-alpha).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1388-9842
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
342-8
pubmed:dateRevised
2011-6-8
pubmed:meshHeading
pubmed:year
2009
pubmed:articleTitle
Impact of exercise training on myostatin expression in the myocardium and skeletal muscle in a chronic heart failure model.
pubmed:affiliation
Clinic of Cardiology, University Leipzig-Heart Center Leipzig, Strümpellstrasse 39, D-04289 Leipzig, Germany. karsten.lenk@med.uni-leipzig.de
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't